Epstein-Barr Virus

نویسنده

  • P. GERBER
چکیده

(ii) the DNA of Ch-LCL contained sequences homologous to approximately 35 to 45% of human EBV; (iii) Ch-LCL contained an intranuclear antigen, Ch-NA, that could be identified with some chimpanzee or orangutan serum in anticomplimentary immunofluorescence assays; and (iv) treatment of Ch-LCL with iododeoxyuridine resulted in expression of new antigenic activity that reacted with EA+ but not EAhuman sera. Two lines of evidence indicate that the chimpanzee agent, although related to human EBV, is a distinct agent: (i) ChNA was antigenically distinct from EBV-related nuclear antigen (EBNA) and EBNA induced in chimpanzee cells by EBV infection although it cross-reacts to

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تاریخ انتشار 2003